Reversible delayed hypoxic leukoencephalopathy associated with methadone overdose

Authors

  • William D. Freeman Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL
  • Scott C. Palmer Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.), Mayo Clinic, Jacksonville, FL
  • Michelle L. Freeman Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL
  • Kevin M. Barrett Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL

Abstract

A 42-year-old man developed coma and hypoxemic respiratory arrestafter snorting and ingesting methadone and required transient intubationand mechanical ventilation in the emergency department (ED). Hewas given naloxone intravenously, woke up and was extubated.

Author Biographies

  • William D. Freeman, Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL
  • Scott C. Palmer, Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.), Mayo Clinic, Jacksonville, FL
  • Michelle L. Freeman, Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL
  • Kevin M. Barrett, Department of Neurology (W.D.F., S.C.P., K.M.B.), Department of Critical Care (M.L.F.) Mayo Clinic, Jacksonville, FL

References

Filley CM, Kleinschmidt-DeMasters BK. Toxic leukoencephalopathy. N Engl J Med. 2001;345(6):425-32.

Keogh CF, Andrews GT, Spacey SD, Forkheim KE, Graeb DA. Neuroimaging features of heroin inhalation toxicity: “chasing the dragon.” AJR Am J Roentgenol. 2003;180(3):847-50.

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Published

12.05.2010

Issue

Vol. 39 No. 1 (2010)

Section

Images in Clinical Medicine

How to Cite

Reversible delayed hypoxic leukoencephalopathy associated with methadone overdose. (2010). Acta Medica Academica, 39(1), 80. https://ama.ba/index.php/ama/article/view/78

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