Different Influence of Anticholinesterase Poissons Given on Serose or Mucose Side of Isolated Innervated Stomach

Authors

  • Seid Huković
  • Kamenko Brankov
  • Svetozar Miletić

DOI:

https://doi.org/10.5644/Radovi.154

Abstract

Spastic poisons applied on serose side of isolated rat's stomach produce the increase of the effect of cholinergic nerves stimulation. Vice versa the anticholinesterases applied on mucose side do not have spastic effect but even produce relaxation. It is suggested that the receptor for excitatory reaction could be near the serose and the receptors for relaxation near mucose. The mucose and other parts of wall of the rats stomach are impermeable for vegetative poisons in vitro.

References

Burn, J. H. and Rand, M. J.: The relation of circulating noradrenaline to the effect of sympathetic stimulation. J. Physiol. (London) 150, 295—305, 1960.

Burnstock, G.: Evolution of the autonomic innervation of visceral and cardiovascular systems in vertebrates. Pharmacolog. Rev. 21, 2A1—324, 1969.

Huković, S. Begić, M. i Radivojević, M.: Izolirani želudac šta­ kora i miša sa pripadajućim nervima kao model-sistem za ispitivanja u farmakologiji, Akademija nauka i umjetnosti SR BiH, Radovi 75, 111—118, 1970.

Huković, S. and H al as moller, I.: The effect of Application of serotonine and other drugs on mucose and serose membrane on the responses of the isoiated stomach to electrical nerve. Folia Fac. Med. univ. Saraev. 6, 115—125, 1971.

Paton, W. D. M. and Vane, J. R.: An analysis of the responses of the izolated stomach to electrical stimulation and to drugs. J. Physiol. (Lond) 165, 10-16, 1963.

Published

02.07.1972

Issue

Section

Works

How to Cite

Different Influence of Anticholinesterase Poissons Given on Serose or Mucose Side of Isolated Innervated Stomach. (1972). Acta Medica Academica, 16, 59-63. https://doi.org/10.5644/Radovi.154

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