The Effect of Brain Oedema Provoked by Triethyltine Upon Clinical Picture Produced With Some Compounds in Rat
DOI:
https://doi.org/10.5644/Radovi.104Abstract
The brain oedem produced by triethyltine has been used to see its influence on the effect of central activating drugs and electroshock. The responses to the drugs were various, decreased, increased or unchanged.
There was no influence of triethyltine on the effect of nikethamide, amphetamine, strychnine (4 mg/kg) and electroshock. The effect of pentetrazol and tremorine was diminished. The effect of chloral-hydrate, pentobarbitone, chlorpromasine, mephenesine, bulbocapnine and strychnine (9 mg/kg) was increased.
References
P. N. Magee, H. B. Stoner i J. M. Barines: The experimental productiion of oedema in the Central nervous system of the rat by taiethylitin compounds. J. Path. Bac. 73, 107 (1957).
L. Bakay: Morphological and Chemical Studies in Cerebral Edema: Triethyl Tin-Induced Edema. J. neurol. Sci. 2, 52 (1965).
R. Katzman, F. Aleu i Wilson: Furhter Observations on Tniethyltin Edema. Arch. Neurology 9, 178 (1963).
R. M. Torack: The relationship between adenosiinetniphosphates activity and tniethyltin toxioity in the production of cerebral edema of ithe rat. Am. J. of pathology, 46, 245 (1965).
H. Leonhardt: Interzellulares perivaskulares Gehimbdem nach Pentamethylentetrazol ("Cardiazol")-Krampf. Naturwdssenschaften 53, 481 (1966).
S. Hara: Jap. J. Pharmacol. 2, 127 (1953). Citirano prema: G. Zetler: Substanz P, ein Polypeptdd aus Danm und Gehinn mit depressiven, hyperalgetischen und Morphin-antagonistischen Wdrkungen auf das Zentralnervensystem. Arch. exper. Path. u. Pharma'kol. 8, 513 (1956).
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