Immunosuppressive Complications Therapy After the Kidney Transplantation
DOI:
https://doi.org/10.5644/Radovi.237Abstract
As a summary to this report we can say the following:
In a series of 37 transplanted patients the survival rate of recipients and grafts was satisfactory, being 87% that is 73% after five years. The data for the western Europe (the report of the European Dialysing and Transplantation Association the EDTA report for 1982) regarding the survival rate after five years are the following:
of the recipient 91%
of the kidney graft 83%
The number of immunosuppressive complications that we have, especially those of infective kind (27,3%) is much larger than indicated in the data for the western Europe (10%). The reason lies in the lack of our experience regarding the kidney transplantation in general, because
we have been working on this problem for nine years only. The other reason is the impossibility of application of the specific immunosuppressive therapy after the kidney transplantation when we are applying only nonspecific therapy with its strong toxic effect enlarges the number of the tendencies towards the infective complications significantly. On the photo material showed, there are some bizarre forms of it.
References
Tilney, N. L., Strom, T. B., Vineyard, G. V. and Merrill, J. P. (1978): Factors contributing to the declining mortality rate in renal transplantation. N. Engl. J. Med., 299, 1321
Padova, F. D., Morandi, E., Mazzei, D., Palo, G. Q., Baldini L., Bianchi G. (1979): Is long-term immunosupressive treatment neccessary to maintain good kidney graft function? Br. Med. J., 2, 421.
Sheriff, M. H. R., Yahya, T., and Lee, H. A. (1978): Is azathioprine necessary in rena transplantation? Lancet, 1, 118.
Morris, P. J., and Salman, J. R. (1979): Kidney Transplantation. Academic Press-London.
McGeown, M. G., Kennedy, J. A., Longhridge, W. G. G., et Col. (1977): One hundred kidney transplants at the Bclfast City Hospital. Lancet, 2, 648.
Bošković, S., Haračić, M., Ignjatović, Ž., Milošević, A. (1978): Our thre-year experience of the complication of immunosupressive therapy after renal transplantation. Tissue Typing and Kidney Transplant., report, 45—52.
Billinghram, R. E., Brent, L., and Medowar, P. B. (1953): Actively acquired tolerance of foreigen cells. Nature 172, 603.
Tilney, N. L., Graves, M. J., and Strom, T. B. (1978): Prolongation of organ allograft survival by syngereic lymphoid cells. J. Immunol., 121, 1980.
McMichael, A. J., Sasazuki, T. (1977): A Supressor T ccll in the human mixed lymphocyte reaction. J. Exp. Med., 146, 368.
Fabre, J. W. (1976): Enhancement and tolerance. Immunology for Surgeons, 259 (Lancaster: MTP).
Batchelor, J. R., and Welsh, K. J.: (1976): Enhancement of Kidney allograft Survival. Br. Med. Buli, 32, 112.
Howard, R. J., Condie, R. M., Sutherland, D. E. (1977): The tise of antityniphocyte globulin in the treatment of renal alograft rejcction. Transplant., 24, 419—423.
Bošković, S., Haračić, M., Grbić, E. (1978): Uro infekcije kod pacijenata sa transplantiranim bubregom. Acta Chirur. lugosl., Tom 2.
Hill, C. M., Douglas, J. F., Rajkumar, K. V. (1974): Glycosuria and hyperglycaemia after kidney transplantation. Lancet, 2, 490 — 492.
Slavin, S., Reitz, B., Bieber, C. P., Kaplan, H. S., and Strober, S. (1978): Transplantation tolerance in adult rats using total lymphoid irradiation'. permanent survival of skin, heart, and marroiv allografts. J. Exp. Med., 147, 700.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Sreten Bošković
This work is licensed under a Creative Commons Attribution 4.0 International License.
