Acute Salicylism in Childern

Abstract

It was thought necessary to present our experience with this kind of poisoning, since it is probable that new facts about the effect of a salycil ion would extend its use, and by that, the possibility of acute salicylism. On the basis of the pharmaco-dynamic characteristics of salicyltes, a physician must realize the risk of their therapeutic application as well as the length of administering them. The damage which can be caused by a salycil ion is almost as extensive as its therapeutic effect. The question of dosage and the length and rhythm of its administration (daily intake) is one to be decided upon from one patient to the next, bearing in mind the capability of a salicyl ion te accumulate in the tissue and cause sudden poisoning, especially in the dehydrated child. Acute salicylism can develop in an acute form, even following the single dose 500 mg in a dehydrated child. Poisoning in children with the prolonged taking of salicyl are more frequent, since it is a cumulative agens. Ali that influences, its resorption and elimination through the urinary tract increases risk of administration of this agens, which by the wide scope of its use seemingly harmless.