Meningoencephalitis in splenectomized patient caused by concurrent Streptococcus pneumoniae and Herpes simplex virus infection
Keywords:
Concurrent, Meningoencephalitis, Herpes, PneumococcalAbstract
In this paper we have described a meningoencephalitis insplenectomized patient caused contemporaneously by Streptococcuspneumoniae and Herpes simplex virus. The unusualcourse of pneumococcal meningitis accompanied with worseningof the patient’s condition and repeated comatous statusdirected clinical diagnosis to the new etiologic agent of meningoencephalitis.After antibiotic and antiviral therapy thepatient fully recovered.Downloads
References
Hussein AS; Shafran SD. Acute bacterial meningitis in adults. A 12-year review. Medicine (Baltimore). 2000;79:360-8.
Tajiri T, Tate G, Enosawa T, Acita H, Ohine N, Masunaga A, et al. Clinicopathological findings in fulminant-type pneumococcal infection: Report of three autopsy cases. Pathology International. 2007;57: 606-12.
Newland A, Provan D, Myint S. Preventing severe infection after splenectomy. BMJ. 2005; 331: 417-8.
LipkinWI. European consensus on viral encephalitis. Lancet. 1997; 349: 299-300.
Dennett C, Cleator GM, Klapper PE. HSV-1 and HSV-2 in herpes encephalitis: a study of sixtyfour cases in the United Kingdom. J Med Virol. 1997;53: 1-3.
Fleicher T. Evaluation of suspected immunodeficiency. In D. Shlosberg editor. Current Therapy of Infectious Disease. St. Louis: Mosby; 2001. p.318-21.
Cullingford GL, Watkins DN, Watts AD, Mallon DF. Severe late postsplenectomy infection. Br J Surg. 1991;78:716-21.
Machesky K, Cushing R. Overwhelming Postsplenectomy Infection in a Patient With Penicillin-Resistant Streptococcus pneumoniae. Arch Fam Med. 1998;7: 178-80.
Kimberlin D, Whitley R. Herpes Simplex Viruses. In D. Shlosberg editor. Current Therapy of Infectious Disease. St. Louis: Mosby; 2001, p.586-90.
Stevens JG, Cook ML, Jordan MC. Reactivation of latent Herpes simplex virus after pneumococcal pneumonia in mice. Infect Immun. 1975;11:635-9.
Wasay M, Mekan SF, Khalaeni B, Saeed Z, Hassan A, Cheema Z et al. Extra temporal involment in herpes simplex encephalitis. Eur J Neur. 2005; 12:475-9.
Lakeman FD, Whitley RJ. Diagnosis of herpes simplex encephalitis; application of polymerase chain reaction to cerebrospinal fluid from brain–biopsied patients and correlation with disease. J Infect Dis. 1995;171:857-63.
Corless C E, Guiver M, Borrow R, Edwards-Jones V, Fox A. J, Kaczmarski EB. Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in Suspected Cases of Meningitis and Septicaemia using Real-Time PCR. J. Clin. Microbiol. 2001;39:1553-8.
