Isolated Innervated Stomach of Rats and Mice as a Model-Svstem for Pharmacological Research
DOI:
https://doi.org/10.5644/Radovi.140Abstract
The constant electrical stimulation of extrinsic and intrinsic nerves of isolated rats and mice stomach produced the regular contractions of longitudinal smooth muscle. Neurotropic and mucosotropic spastics and spasmolytic modified the effect of nerve stimulations and tonus of the smooth muscle. Acetylcholine, Barium, Physostigmine increased tonus and induced contractions. Morphine, Papaverine, Aminophylline, Benactyzine and Atropine decreased the contractions and tonus of stomach. The vagile nerves control tonus and contractions of stomach muscle more apparent than it was supposed.
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