Leucoencephalitis Subacuta Sclerosans (Van Bogaert)
DOI:
https://doi.org/10.5644/Radovi.95Abstract
The authors present the clinical features and findings of cerebrospinal fluid and EEG obtained by investigations carried out on 20 clinical patients with subacute sclerosing leucoencephalitis at the Sarajevo Clinic of Neuropsychiatry during a period of 9 years (1957—1965). This rather infrequent disease appears mainly in young people (6—15-year-olds being most frequently affected by it) and, as a rule, lasts a few months, less frequently over a year and progresses steadily to a fatal termination, with terminal cachexia and total dementia. The males are more frequently attacked by the disease.
The authors themselves examined 13 out of 15 anatomically verified cases. In six cases Type A acidophilic intranuclear inclusions were found. No one of the cases could be classified as a pure type of Dawson, Pette-Doring or van Bogaert encephalitis. The authors consider that no criteria exist for a distinction between the three types and believe that there is only one ‘type of the disease in which inclusion bodies may occur, sometimes the cortex may be involved to a higher degree, and a greater number of glial nodules may occur at times as a result of microglia reaction.
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