Evidence-based medicine and clinical practice

Mirjana Huić

Abstract


Evidence-based medicine (EBM) is the conscientious, explicit,and judicious use of current best evidence in makingdecision about the care of individual patients. The practiceof evidence-based medicine integrates physician’s individualclinical expertise, best available research evidence, and patientunique values in the process of decision-making aboutthe health-care. It should be accompanied by evidence-basedpatient choice. Evidence-based patient information, patientdecision aids, have been developed to assist patients withdifficult health-related decisions. The rationale of evidencebasedpractice is to improve the quality of care through theidentification and promotion of effective practice and eliminationof practices that are ineffective or harmful. The practiceof EBM involves five essential steps: converting informationneeds into an answerable question (PICO format); findingthe best evidence to answer the question; critical appraisalof the evidence for its validity and usefulness; application ofthe results into clinical practice; and evaluating performance.The practice of EBM should be a part of patients’ daily care.

Keywords


Evidence-based medicine, Evidence-based practice, Evidence-based patient choice, Evidence-based physician- patient relationship, Patient decision aids

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References


Sackett DL, Rosemberg WM, Gray JA, Richardson WS. Evidence based medicine: what it is and what it isn’t. BMJ. 1996;312:71-2.

Straus SE, Richardson WS, Glaziou P, Haynes RB, editors. Evidence-based medicine. How to practice and teach EBM. Edinburgh: Elsevier Churchill Livingstone; 2005.

Akobeng AK. Evidence based child health. Principles of evidence based medicine. Arch Dis Child. 2005;90:837-40.

Glasziou P, Del Mar C, Salisbury J, editors. Evidence- based medicine workbook. London: BMJ publishing group; 2003.

Guyatt G, Rennie D, editors. Users guides to the medical literature. Chicago: American Medical Association; 2002.

Holmes-Rovner M, Liewellyn-Thomas H, Entwistle V, Coulter A, O’Connor A, Rovner DR. Patient choice modules for summaries of clinical effectiveness: a proposal. BMJ. 2001;322:664-67.

O’Connor AM, et al. Decision aids for people facing health treatment or screening decisions. The Cochrane Database of Systematic Reviews, 2004, Issue 1.

O’Donnell S, Cranney A, Jacobsen MJ, Graham ID, O’Connor AM, Tugwell P. Understanding and overcoming the barriers of implementing patient decision aids in clinical practice. J Eval Clin Pract. 2006;12:174-81.

Dwan K, Altman DG, Arnaiz JA, Bloom J, Chan A-W, Cronin E, et al. Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias. PLoS ONE 2008;3:e3081.

Lee K, Bacchetti P, Sim I. Publication of clinical trials supporting successful new drug applications: A literature analysis. PLoS Med. 2008;5:e191.

De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, et al. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Croat Med J. 2004;45:531-2.

De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, et al. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Croat Med J. 2005;46:499-501.

Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, et al. Clinical trial registration: looking back and moving ahead. Croat Med J. 2007;48:289-91.

Krleža-Jerić K. International dialogue on the public reporting of clinical trial outcome and results – PROCTOR meeting. Croat Med J. 2008;49:267-8.

Marušić A, Huić M. Registration of Clinical Trials Still Moving Ahead – Update to Uniform Requirements for Manuscripts Submitted to Biomedical Journals. Croat Med J. 2008;49:582-5.


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