Molecular Imaging

Faruk Dalagija, Amela Mornjaković, Irmina Sefić

Abstract


Molecular imaging is a new medical discipline that integrates cell biology, molecular biology and diagnostic imaging. It is generally defined as the in vivo characterization and measurement of biological processes at the cellular or molecular level. Compared to conventional diagnostic imaging, it examines the specific molecular abnormalities that are the origin of disease, rather than providing images of the resulting condition. Molecular imaging has two basic applications. The first is diagnostic imaging, which is used to determine the location and extent of targeted molecules specific to the disease being assessed. The second is therapy, which is used to treat specific disease–targeted olecules. The basic data about molecular imaging are reviewed in this paper.

Keywords


Diagnostic Imaging; Positron-Emission Tomography, Magnetic Resonance Imaging; Molecular Biology; Review.

Full Text:

PDF

References


Rollo FD. Molecular imaging: an overview and clinical applications. Radiol Manage. 2003; 25(3): 28-32.

Weissleder R, Mahmood U. Molecular imaging. Radiology. 2001; 219: 316-33.

Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003; 17(5): 545-80.

Bachert P, Schroder L. Magnetresonanzspektroskopie. Teil 1. Grundlagen. Radiologe. 2003; 43(12): 1113-26.

Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer. 2002; 2(9): 683-93.

Dobrucki LW, Sinusas AJ. Molecular imaging. A new approach to nuclear cardiology. Q J Nucl Med Mol Imaging. 2005; 49(1): 106-15.

Hicks RJ. Functional imaging techniques for evaluation of sarcomas. Cancer Imaging. 2005; 5(1): 58-65.

Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S. van de Kaa CH, et al. Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N Engl J Med. 2003; 348(25): 2491-9.


Refbacks

  • There are currently no refbacks.


2016 Department of Medical Sciences, Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina. All rights reserved.
 
The full text of articles published in this journal can be used free of charge for personal and educational purposes while respecting authors and publishers’ copyrights. For commercial purposes no part of this journal may be reproduced without the written permission of the publisher.