Clinical updates on diagnosing glutensensitive enteropathy

Faruk Hadziselimovic, Annemarie Bürgin-Wolff

Abstract


In the last twenty years serology for the diagnosis of coeliac disease hasimproved substantially. As the result of our serological studies in 1998we proposed a gentle, low-risk, and cost eff ective algorithm for diagnosingvarious forms of gluten sensitive enteropathy, using a combinationof diff erent antibody determinations, namely IgA Endomysiumantibodies (EMA), Tissue-transglutaminase antibodies (IgA anti tTG,IgG anti tTG), IgA-and IgG antigliadin-antibodies. Performing routinelyserologic testing contributes to a decreased rate of endoscopicinterventions and improves the quality of the patient’s life.

Keywords


Coeliac disease; Antibodies; Intestinal biopsy; Diagnosis

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References


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